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Thursday, September 09, 2010

Software: Computer Algorithms Implemented:

 

            Sielken & Associates develops software primarily for internal and client use and does not for distribute software for sales purposes.

 

 

Risk Characterization Tools:

 

  1. Determines a distributional characterization of the added cancer risk at user-specified dose levels and explicitly incorporates weights on the relative plausibility of competing alternatives in a weight-of-evidence analysis of the current state of knowledge concerning the carcinogenic effects of a specified substance.
                       
    UNRAVEL

  2. Determines a distributional characterization of the reference dose (RfD) or reference concentration (RfC) for the noncancer health effects of a specific substance.  Facilitates a weight-of-evidence analysis of the competing indicator doses and uncertainty factor characterizations and helps determine a probability distribution characterization of the RfD or RfC that explicitly incorporates the user-specified weights indicating the relative plausibility of the competing alternatives.
                       
    UNRAVELN