Website Outline
1. Litigation Support1.1 Capabilities1.2 Risks in Perspective1.3 Plaintiff Viewer1.4 Test Plaintiff Selection 1.4.1 Advantages of Random Test Plaintiff Selection1.5 Example Activities1.6 Litigation History
2. Regulatory Risk Assessment2.1 Risk Assessments Developed Under Regulatory Guidelines2.2 Risks from Naturally Occurring Carcinogens and Human Activities2.3 Example Activities2.4 Brief Overview of Recent Regulatory History in the USA 2.4.1 Summary 2.4.2 Timeline for Establishment of Agencies 2.4.3 Statutory Timeline 2.4.4 Supplemental Regulations 2.4.5 Highlights for Some Agencies 2.4.6 History of the California Environmental Protection Agency 2.4.7 History of Food Regulation
3. Human Health Risk Assessment3.1 Quantitative Risk Assessment and Statistical Analysis3.2 Importance of Dose and Dose-Response Relationships3.3 Misuse of Regulatory Upper-Bound Risk Characterizations3.4 Risk Characterization Choices and Risk Exaggeration3.5 A Better Approach to Cancer Risk Characterization3.6 Overview of Background, Motivation, and Statistical Methods for Margin-of-Exposure Characterizations of Cancer Risks 3.6.1 Importance of Dose 3.6.2 Dose-Response Modeling 3.6.3 Dose-Response Models 3.6.4 Maximum Likelihood Estimation 3.6.5 Multistage Model 3.6.6 Example of Fitted Multistage Model 3.6.7 Potency 3.6.8 Linearized Multistage Model 3.6.9 Overstatement of Risks by the Linearized Multistage Model 3.6.10 Adverse Impacts of the Variability in the Magnitude of the Bias in the Linearized Multistage Model's Overstatement of Risks 3.6.11 Non-Responsiveness of the Linearized Multistage Model to Data 3.6.12 Ranking Relative Risks 3.6.13 Added Risk versus Extra Risk 3.6.14 Need for a Better Dose-Response Characterization 3.6.15 Better Dose-Response Characterization 3.6.16 Benchmark Doses 3.6.17 Responsiveness of Benchmark Doses Data Versus the Relative Non-Responsiveness of the Regulatory Upper-Bound Potency Q1* based on the Linearized Multistage Model 3.6.18 Recommended Dose-Response Characterization 3.6.19 Margin-of-Exposure Characterizations 3.6.20 Conclusion 3.6.21 Figures 1 to 163.7 Innovative Risk Assessment3.8 Components of High-to-Low-Dose Extrapolation and Dose-Response Modeling3.9 Probabilistic Exposure Assessment3.10 Aggregate Risk Assessment3.11 Cumulative Risk Assessment3.12 Example Activities
4. Statistics4.1 General Statistical Expertise4.2 Monte Carlo Simulation Techniques4.3 Scientific Notation
5. Software5.1 Dose-Response Modeling Tools5.2 Exposure Assessment Tools5.3 Risk Characterization Tools5.4 Statistical Tools5.5 Operations Research and Mathematical Programming Algorithms5.6 Predecessor Website